Unlike mammals, zebrafish regenerate following retina damage from a resident adult stem cell (Müller glia). Dissecting the mechanisms that zebrafish use could lead to new therapeutic targets to treat retinal diseases. Patton and colleagues have discovered a mechanism by which decreased GABA levels are sensed by Müller glia to initiate a regenerative response.

Molecular and Cellular Biology. 2 (9): 1096–103. doi:10.1128/mcb.2.9.1096. PMC 369902. PMID 6983647. Muller HJ (July 1927). "Artificial Transmutation of the

detrimental effects, is essential for the development of Supporting cells that extend through the retina to form its inner and outer limiting membranes. 2014-07-08 · The Müller cell, acting as a wavelength-dependent optical fibre, concentrates the red–green part of the spectrum inside the cells, to reach the cones, while allowing blue–violet light to leak disorder as “familial ILM dystrophy”, it was defined as “Muller cell sheen dystrophy” in the later reports, owing to suspects that the primary affected part was Muller cells [2]. Trichromatic color vision deficiency is a relatively frequent trichromatic disorder in which visual acuity (VA) is spared and photophobia and nystagmus are absent. Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate transport, Müller cells control the composition of the extracellular space fluid. Muller's new medication, marketed as Lupuzor and expected to be launched in 2018, silences only so-called "T-cells" associated with lupus while leaving healthy defences intact. Muller and her team at CNRS achieved their breakthrough in the early 2000s as they were researching the effects of synthetic peptides on immune responses.

Muller cells

Also in retina of Eberhart Zrenner MD, in Clinical Ocular Toxicology, 2008. Damage to glial cells. The retina has several types of glial cells: Mueller cells, oligodendrocytes and astrocytes.Mueller cells are important for glutamate metabolism (in the uptake of the transmitter released by photoreceptors), as well as for the storage of calcium ions. 1992-08-01 Müller cells constitute the dominant glial cell type in the retina.

This disorder is considered by some to result from a primary defect in Muller cells resulting in permeability defects on the retinal surface. Evidence for this

Learn more about the evolution of and the people involved in cell theory. Advertisement By: William Harris The discovery of the cell was made possible by the in Cell theory is the scientific theory that describes the properties of cells, primarily that the cell is the basic unit of life, and all living things are m Cell theory is the scientific theory that describes the properties of cells, primari Cell membranes contain and protect the contents of the cell.

Muller cells provide homeostatic and metabolic support for retinal neurons, like the ganglions and starburst amacrines we map in Eyewire. They are retinal glial cells that wrap around the cells that form capillaries, endothelial cells and pericytes, and constitute the majority of the non-neuronal volume of the retina.

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Müller glia are a type of glial cell found in the specifically in the retina. The word “glia” is derived from the Greek word meaning “glue,” owing to their appearance of gluing together cells in the nervous system. Müller glia can be seen spanning the entire retina and touching all cell types. Müller cells, the major glial cells of retina, are responsible for retinal redox homeostasis and metabolic support of retinal neurons (Reichenbach and Bringmann, 2013).
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After maturation, most radial glia disappear and transform into stellate astrocytes, although radial glial cells remain in the retina (Müller cells).
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These cells, Müller cells, are radial glial cells in the inner vertebrate retina, which have a cylindrical, fiber-like shape (their original name was “radial fibers of Müller”) (10). They fulfill a wide range of physiological functions to support the functioning and survival of retinal neurons (11).

住所：東京都港区北青山2丁目12−4. Description. Müller glia, or Müller cells, are glial cells found in the retina, which serve as support cells for the neurons of the retina as all glial cells do.. However, following injury to the retina, it has been shown in zebrafish that Müller glia undergo dedifferentiation into multipotent progenitor cells.

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Müller cells are specialized radial glial cells which span the entire thickness of the neural retina, from the subretinal space to the vitreal surface (Fig. 17.1A, B). The somata of the cells are located in the inner nuclear layer, and two stem (trunk) processes radiate from the soma in opposite directions.

Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate transport, Müller cells control the composition of the extracellular space fluid. Müller cells provide trophic and anti-oxidative support of photoreceptors Muller (radial glial) cells span the entire thickness of the retina, and contact and ensheath every type of neuronal cell body and process. This morphological relationship is reflected by a multitude of functional interactions between retinal neurons and Muller cells, including extracellular ion homeostasis and glutamate recycling by Muller cells. Muller cells provide homeostatic and metabolic support for retinal neurons, like the ganglions and starburst amacrines we map in Eyewire. They are retinal glial cells that wrap around the cells that form capillaries, endothelial cells and pericytes, and constitute the majority of the non-neuronal volume of the retina.